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- 產(chǎn)品名稱： Research Grade IPH4301
- 產(chǎn)品貨號： CSD00838
- 貨期： 現(xiàn)貨
- 價格與訂購： 2480
- 數(shù)量：
庫存： 100
- 規(guī)格： 100μg 200μg 1mg
- 產(chǎn)品信息
- 如何訂購
貨號（Catalog No.）
CSD00838
通用名INN
IPH4301
純度(Purity)
>95%
電泳圖（SDS-PAGE image）
濃度( Concentration)
1.25mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
生物活性
產(chǎn)品描述(Description)
IPH4301 is a program to develop a first in class anti MICA/B therapeutic antibody in oncology. MICA/B is a highly polymorphic ligand of the NK cell activating receptor NKG2D.
靶點(diǎn);物種(Specificity target name;species)
MICA/B[Homo sapiens]
靶點(diǎn)背景信息(Target information)
MICA and MICB, and ULPB1-6, are ligands for NKG2D, an activating receptor expressed on NK cells and subsets of T cells. Expression of MICA and MICB is induced by cellular stress in transformed tumor cells, upon infections or at sites of chronic inflammation. Their expression is tightly regulated by complex mechanisms both at the mRNA and protein levels. As markers of cellular stress and tumorigenesis, MICA and MICB proteins are attractive candidates for targeting by a cytotoxic antibody.
種類(Species)
Humanized
受體鑒定(Receptor identification)
Human IgG1
化學(xué)信息
分子量(MV)
150000.00 Da
存儲條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .
地 址：
產(chǎn)品銷售：
E - mail ：
郵 編：
Amily
