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- 產(chǎn)品名稱： Succinylated Lysine Rabbit Polyclonal Antibody
- 產(chǎn)品貨號(hào)： CS3089
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購(gòu)： 2398
- 數(shù)量：
庫(kù)存： 100
- 規(guī)格： 100μl 1ml
- 產(chǎn)品信息
- 如何訂購(gòu)
Attribute
Rabbit Polyclonal Antibody
Isotype
IgG
Purity
Antigen Affinity Purification
Application
WB, IP, ELISA
Reactivity
Succinylated Protein
Immunogen
Succinylated BSA
Buffer
PBS with 0.1% sodium azide and 50% glycerol, pH 7.2
Storage
Store at -20℃. Do not aliquot
Recommended Dilution
WB: 1:1000-2000 IP: 1:5000-10000
Background
Succinylation is a posttranslational modification where a succinyl group (-CO-CH2-CH2-CO2H) is added to a lysine residue of a protein molecule. This modification is found in many proteins, including histones. The potential role of succinylation is under investigation, but as addition of succinyl group changes lysine's charge from +1 to ?1 (at physiological pH) and introduces a relatively large structural moiety (100 Da), bigger than acetylation (42 Da) or methylation (14 Da), it is expected to lead to more significant changes in protein structure and function. By analogy to acetylation, it has been suggested that succinyl-CoA is the cofactor of enzyme-mediated lysine succinylation.
Note
For research use only .
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