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  • 產品名稱: Recombinant Human P4HB protein
  • 產品貨號: CSP01944
  • 貨期: 現(xiàn)貨
  • 價格與訂購: 1800
  • 數(shù)量:
    庫存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產品信息
  • 如何訂購
    概述(Summary)
    英文全稱
    Recombinant Human P4HB protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構建(Construction)
    A DNA sequence encoding the human P4HB (Phe216-Gly465) was fused with GST tag
    Accession #
    P07237
    表達宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預測分子量(Predicted Molecular Mass)
    52.74 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP. Receptor for LGALS9; the interaction retains P4HB at the cell surface of Th2 T helper cells, increasing disulfide reductase activity at the plasma membrane, altering the plasma membrane redox state and enhancing cell migration .
    分子別名(Alternative Names)
    Protein disulfide-isomerase,PDI,Cellular thyroid hormone-binding protein,Prolyl 4-hydroxylase subunit beta,p55.
    Note
    For research use only .
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