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  • 產(chǎn)品名稱: Recombinant Human Desmin protein
  • 產(chǎn)品貨號(hào): CSP00009
  • 貨期: 現(xiàn)貨
  • 價(jià)格與訂購(gòu): 1800
  • 數(shù)量:
    庫(kù)存: 100
  • 規(guī)格: 50μg 100μg 1mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    概述(Summary)
    英文全稱
    Recombinant Human Desmin protein
    純度(Purity)
    >90% as determined by SDS-PAGE
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    蛋白構(gòu)建(Construction)
    A DNA sequence encoding the human Desmin (Met1-Leu470) was fused with His tag
    Accession #
    P17661
    表達(dá)宿主(Host)
    E.coli
    種屬(Species)
    Homo sapiens (Human)
    預(yù)測(cè)分子量(Predicted Molecular Mass)
    53.46 kDa
    制劑(Formulation)
    Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
    運(yùn)輸方式(Shipping)
    In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
    穩(wěn)定性&儲(chǔ)存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    復(fù)溶(Reconstitution)
    Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
    背景(Background)
    背景介紹
    Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. May act as a sarcomeric microtubule-anchoring protein: specifically associates with detyrosinated tubulin-alpha chains, leading to buckled microtubules and mechanical resistance to contraction. Contributes to the transcriptional regulation of the NKX2-5 gene in cardiac progenitor cells during a short period of cardiomyogenesis and in cardiac side population stem cells in the adult. Plays a role in maintaining an optimal conformation of nebulette (NEB) on heart muscle sarcomeres to bind and recruit cardiac alpha-actin.
    分子別名(Alternative Names)
    DES
    Note
    For research use only .
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