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- 產(chǎn)品名稱： Research Grade Coltuximab
- 產(chǎn)品貨號： CSDHD10801
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購： 2480
- 數(shù)量：
庫存： 100
- 規(guī)格： 100μg
- 產(chǎn)品信息
- 如何訂購
Description
Coltuximab ravtansine (SAR3419) is an antibody-drug conjugate (ADC) targeting CD19 created by conjugating a derivative of the potent microtubule-acting cytotoxic agent, maytansine, to a version of the anti-CD19 antibody, anti-B4, that was humanized as an IgG1 by variable domain resurfacing. Four different linker-maytansinoid constructs were synthesized (average ～3.5 maytansinoids/antibody for each) to evaluate the impact of linker-payload design on the activity of the maytansinoid-ADCs targeting CD19. Anti-CD19 humanized monoclonal antibody conjugated to DM4.
Catalog No.
CSDHD10801
Host species
Chimeric
Species reactivity
Human
Form
Liquid
Storage buffer
PBS buffer pH 7.5
Concentration
1mg/ml
Purity
>95%
Clonality
Monoclonal
Isotype
IgG1-kappa
Applications
Research Grade Coltuximab Biosimilar
Target
CD19,Differentiation antigen CD19,T-cell surface antigen Leu-12,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4
Purification
Protein A or G purified from cell culture supernatant.
Endotoxin level
Please contact with the lab for this information.
Expression system
Mammalian cells
Accession
P15391
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
Alternative Names
CD19, SAR3419, CAS: 1269764-99-9
Data Image
SDS PAGE for Coltuximab Ravtansine
Note
For research use only .
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Amily
