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  • 產(chǎn)品名稱: Recombinant Human PIVKA-II/Prothrombin protein,C- His Tag
  • 產(chǎn)品貨號(hào): CSMP00554HU
  • 貨期: 現(xiàn)貨
  • 價(jià)格與訂購(gòu): 2880
  • 數(shù)量:
    庫(kù)存: 100
  • 規(guī)格:
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    產(chǎn)品名稱(Product name)
    Recombinant Human PIVKA-II/Prothrombin protein,C- His Tag
    貨號(hào)(Catalog#)
    CSMP00554HU
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    描述(description)
    A DNA sequence encoding the human F2(Met1-Glu622)with C-terminal His Tag
    表達(dá)系統(tǒng)(Expression system)
    Mammalian cells
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    種屬(Species)
    Homo sapiens (Human)
    Accession #
    P00734
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    別名(Alternative names)
    Coagulation factor II
    實(shí)際分子量(Actual Molecular Mass)
    85kDa
    純度(Purity)
    >90% by SDS-PAGE
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    制劑(Formulation)
    Supplied as solution form in PBS, pH7.5/ Supplied as lyophilized from PBS, pH7.5
    運(yùn)輸方式(Shipping)
    In general, proteins are shipped out with blue ice unless customers require otherwise.
    穩(wěn)定性&儲(chǔ)存(Stability &Storage)
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
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    復(fù)溶(Reconstitution)
    Please refer to the instraction in the hard copy of COA.icon
    應(yīng)用(Application)
    Calibrator or standard in ELISA, WB, IHC and other possible application
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    背景(Background)
    Protein Induced by Vitamin K Absence or Antagonist-II (PIVKA-II), also known as Des-γ-carboxy-prothrombin (DCP), is an abnormal form of prothrombin. Normally, the prothrombin’s 10 glutamic acid residues (Glu) in the γ-carboxyglutamic acid (Gla) domain at positions 6, 7, 14, 16, 19, 20,25, 26, 29 and 32 are γ-carboxylated to Gla by vitamin-K dependent γ- glutamyl carboxylase in the liver and then secreted into plasma. In patients with hepatocellular carcinoma (HCC), γ-carboxylation of prothrombin is impaired so that PIVKA-II is formed instead of prothrombin. PIVKA-II is considered as is an efficient biomarker specific for HCC
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    Note
    For research use only .
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