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  • 產(chǎn)品名稱: Research Grade Enfortumab(恩弗妥單抗)
  • 產(chǎn)品貨號: CSD00330
  • 貨期: 現(xiàn)貨
  • 價(jià)格與訂購: 2480
  • 數(shù)量:
    庫存: 100
  • 規(guī)格: 100μg
  • 產(chǎn)品信息
  • 如何訂購
    貨號(Catalog No.)
    CSD00330
    通用名INN
    Enfortumab
    純度(Purity)
    >95%
    濃度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    產(chǎn)品描述(Description)
    Enfortumab vedotin is an antibody-drug conjugate used in the treatment of patients with advanced, treatment-resistant urothelial cancers.It is comprised of a fully human monoclonal antibody targeted against Nectin-4 and a microtubule-disrupting chemotherapeutic agent, monomethyl auristatin E (MMAE), joined by a protease-cleavable link.It is similar to brentuximab vedotin, another antibody conjugated with MMAE that targets CD-30 instead of Nectin-4.The clinical development of enfortumab vedotin was the result of a collaboration between Astellas Pharma and Seattle Genetics and it was first approved for use in the United States in December 2019 under the brand name PadcevTM.
    別名(Alternative names)
    AGS-22CE,AGS-22M,AGS-22M6E,unconjugated:AGS-22C3 or AGSM6
    靶點(diǎn);物種(Specificity target name;species)
    PVRL4[Homo sapiens]
    種類(Species)
    Homo sapiens
    受體鑒定(Receptor identification)
    IgG1-kappa
    CAS
    1346452-25-2
    存儲(chǔ)條件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .
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