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  • 產品名稱: Research Grade Aselizumab ( 阿塞珠單抗 )
  • 產品貨號: CSD00177
  • 貨期: 現貨
  • 價格與訂購: 2480
  • 數量:
    庫存: 100
  • 規(guī)格: 100μg
  • 產品信息
  • 如何訂購
    貨號(Catalog No.)
    CSD00177
    通用名INN
    Aselizumab
    純度(Purity)
    >95%
    濃度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    內毒素(Endotoxin level)
    Please contact with the lab for this information.
    別名(Alternative names)
    HuDreg-55
    靶點;物種(Specificity target name;species)
    SELL/CD62L [Homo sapiens]
    活性研究(體外/體內研究)(Activity in vitro)
    Dexamethasone (Hexadecadrol) regulates several transcription factors, including activator protein-1, nuclear factor-AT, and nuclear factor-kB, leading to the activation and repression of key genes involved in the inflammatory response.
    Dexamethasone potently inhibits granulocyte-macrophage colony stimulating factor (GM-CSF) release from A549 cells with EC50 of 2.2 nM. Dexamethasone (EC50=36 nM) induces transcription of the β2-receptor is found to correlate with glucocorticoid receptor (GR) DNA binding and occurred at 10-100 fold higher concentrations than the inhibition of GM-CSF release. Dexamethasone (IC50=0.5 nM) inhibits a 3×κB (NF-κB, IκBα, and I-κBβ), which is associated with inhibition of GM-CSF release.
    種類(Species)
    Humanized
    受體鑒定(Receptor identification)
    IgG4-nd
    CAS
    395639-53-9
    存儲條件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .

     

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