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- 產(chǎn)品名稱： Research Grade Ruplizumab ( 盧利珠單抗 )
- 產(chǎn)品貨號(hào)： CSD00002
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購(gòu)： 2480
- 數(shù)量：
庫(kù)存： 100
- 規(guī)格： 100μg
- 產(chǎn)品信息
- 如何訂購(gòu)
貨號(hào)（Catalog No.）
CSD00002
通用名INN
Ruplizumab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
產(chǎn)品描述(Description)
Ruplizumab is a humanized monoclonal antibody used as an immunosuppressive drug and is a component of Antova.Ruplizumab is an anti-CD40L monoclonal antibody.The binding of CD40 to its ligand,CD40L is a critical element in T cell activation.In systemic lupus erythematosus,CD40L is over-expressed on T cells, B cells and monocytes.
別名(Alternative names)
BG-9588,hu5c8
靶點(diǎn);物種(Specificity target name;species)
CD40LG[Homo sapiens]
靶點(diǎn)背景信息(Target information)
Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
種類(Species)
Humanized
受體鑒定(Receptor identification)
IgG1-kappa
分子量(MV)
145448.00 Da
CAS
220651-94-5
存儲(chǔ)條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .
地 址：
產(chǎn)品銷售：
E - mail ：
郵 編：
Amily
