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- 產(chǎn)品名稱： Anti NFE2L2(E79K) Mouse Monoclonal Antibody
- 產(chǎn)品貨號(hào)： CST26337
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購： 4800
- 數(shù)量：
庫存： 5
- 規(guī)格： 100μg
- 產(chǎn)品信息
- 如何訂購
Catalog Number
CST26337
Gene Symbol
NFE2L2, NRF2
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Description
Anti NFE2L2(E79K) Mouse Monoclonal Antibody
Background
NFE2L2 protein is encoded by NFE2L2 gene. It is a basic leucine zipper protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. Several drugs that stimulate the NFE2L2 pathway are being studied for treatment of diseases that are caused by oxidative stress.
Immunogen
A synthetic peptide from the internal region of NFE2L2 which includes the mutation of E79K, human origin.
Applications
ELISA, WB, IHC
Recommended Dilutions
ELISA: 1:1000-1:2000
WB: 1:500-1:1000
IHC: 1:50-1:100
Concentration
1 mg/ml
Host
mouse
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Format
Liquid
Clonality
Monoclonal
Purity
Purified from ascites
Preservative
no
Constituents
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity
Recognizes E79K mutant, but not wild-type NFE2L2 of vertebrates.
Immunoprecipitation/Western Blot
Western blot analysis of recombinant NFE2L2(E79K) and wildtype proteins. Purified His-tagged NFE2L2(E79K) protein (lane2) and corresponding wild-type protein (lane1) were blotted with Anti NFE2L2(E79K) monoclonal antibody (Cat. #26337).
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Immunofluorescence:
Immunofluorescence of cells expressing NFE2L2 proteins with Anti NFE2L2(E79K) antibody. HEK293T cells were transfected with pCDNA3-GFP-NFE2L2(E79K) plasmid, pCDNA3-GFP NFE2L2(WT) plasmid, or pCDNA3-GFP NFE2L2(E79Q) plasmid, then fixed and stained with Anti NFE2L2(E79K) monoclonal antibody (Cat. #26337).
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Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles
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Note
For Research Use Only.
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