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- 產(chǎn)品名稱： Anti Active Rap1 Mouse Monoclonal Antibody
- 產(chǎn)品貨號： CST26912
- 貨期： 現(xiàn)貨
- 價格與訂購： 4800
- 數(shù)量：
庫存： 5
- 規(guī)格： 100μg
- 產(chǎn)品信息
- 如何訂購
Catalog Number
CST26912
Gene Symbol
RAP1
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Description
Anti Active Rap1 Mouse Monoclonal Antibody
Background
Small GTPases are a super-family of cellular signaling regulators. Rap family members (Rap1A, Rap1B, Rap2A, Rap2B, and Rap2C) are Ras-like GTPases that regulate cell proliferation, differentiation, apoptosis and adhesion mechanisms. Rap1 (Ras-proximate-1) regulates apoptosis through interaction with two MAP3K effectors of the MEK/ERK MAP-kinase pathway, Raf-1 and B-Raf. Rap1 regulates cell adhesion mechanisms through effector molecules such as the integrins and cadherins.
Immunogen
Recombinant full length protein of active Rap1.
Applications
IP, IHC
Recommended Dilutions
1 μg for ~2 mg total cellular proteins for IP
1:100 dilution for IHC, IF
Concentration
1 mg/ml
Host
mouse
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Format
Liquid
Clonality
Monoclonal
Isotype
IgG
Purity
Purified from ascites
Preservative
no
Constituents
PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Anti-active Rap1 antibody recognizes active Rap1 of vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
Species Reactivity
Anti active Rab7 antibody recognizes active Rab7 proteins of vertebrates.
Immunoprecipitation/Western Blot
Rap1 activation assay. Purified Rap1 proteins were immunoprecipitated after treated with GDP (lane 1) or GTPγS (lane 2). Immunoprecipitation was done with the anti-active Rap1 monoclonal antibody (Cat. No. 26912). Immunoblot was with an anti-Rap1 polyclonal antibody (Cat. No. 21104).
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Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles
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Note
For Research Use Only.
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