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- 產(chǎn)品名稱： Furimazine
- 產(chǎn)品貨號： CS15359
- 貨期： 現(xiàn)貨
- 價格與訂購： 2400
- 數(shù)量：
庫存： 5
- 規(guī)格： 1mg
- 產(chǎn)品信息
- 如何訂購
貨號（Catalog No.）
CS15359
別名
PBI 3939
純度(Purity）
97.57%
產(chǎn)品描述(Description)
Furimazine is an imidazopyrazinone substrate. NanoLuc (Nluc) paired with Furimazine produced 2.5 million-fold brighter luminescence in mammalian cells relative to Oluc-19 with Coelenterazine.
體外活性
Furimazine is a Coelenterazine analogue. Measurement of luminescence intensity from cells expressing Nluc reveals that maximal signal is attained at about 10-20 μM Furimazine[1]. The apparent Km for purified NanoLuc (Nluc) using either Furimazine or Coelenterazine is ~10 μM, while the maximum luminescence (i.e., apparent Vmax) is ~30-fold higher for Furimazine than for native Coelenterazine.
分子式
C24H19N3O2
分子量
381.435
參考文獻
[1]Hall MP, et al. Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate. ACS Chem Biol. 2012 Nov 16;7(11):1848-57.
儲存和溶解度
DMSO:100 mg/mL (262.17 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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Amily
